• The prospects of the use of this novel

  2021-02-01

  

  The prospects of the use of this novel approach for the selective local thermo-activation of enzymes include biomedical and biotechnological applications. As NPs could be engineered to gain access to Darifenacin HBr receptor through the endosomal compartment [47] or through non-endocytotic pathways

• br Halogenases Enzymatic C H activation leading to halogenat

  2021-02-01

  

  Halogenases Enzymatic C–H activation leading to halogenation is another emerging area in biocatalysis [55,56]. Incorporation of halogen atoms during medicinal chemistry eff ;orts is a well-established practice, presenting an effective means to control the molecule’s bioactivity and physicochemical

• br Methods br Results br Discussion

  2021-02-01

  

  Methods Results Discussion I/R induces oxidative stress and increases the intracellular levels of ROS, resulting in tissue damage [31]. ROS is generated by mitochondrial electron transport chain, nicotinamide leukotriene receptor antagonists dinucleotide phosphate (NADPH) oxidase complex,

• br Material and methods br

  2021-02-01

  

  Material and methods Results and discussion Conclusion The gene encoding the Bos taurus muscle enolase enzyme was successfully isolated and cloned in this study. Optimization of the cloning, gene igf1r inhibitor and purification was performed and protein elution at 95% purity was achieved.

• br Ubiquitination and deubiquitination pathways Ubiquitinati

  2021-02-01

  

  Ubiquitination and deubiquitination pathways Ubiquitination is a part of the post-translational modification (PTM) process. Ubiquitination affects proteins in various ways, but its main functions are to signal protein degradation via the 26S proteasome, modify cellular location of proteins, affec

• br Conclusion As far as we know this work constituted

  2021-02-01

  

  Conclusion As far as we know, this work constituted the first use of silver nitrate staining and sequential FISH in V. vinifera. This technique allowed the unequivocal identification of Ag-NORs and corresponding rDNA loci. Besides, silver nitrate staining and sequential FISH may bring new insigh

• br Conclusions There is significant

  2021-02-01

  

  Conclusions There is significant interest in understanding the contribution of biological mechanisms to the non-linear/bilinear dose–response curves for DNA-reactive agents. Model monofunctional alkylating agents have datasets amenable to PoD determination for genotoxic effects in both in vitro a

• Introduction Cyclin dependent kinases CDKs are a family of

  2021-02-01

  

  Introduction Cyclin dependent kinases (CDKs) are a family of proline-directed serine/threonine kinases with roles in regulation of crucial cellular processes such as FK-228 and transcription [1]. One of the unifying features of this family is its dependence on association with cyclins/cyclin-like

• Recently we have observed that pharmacological PPAR and

  2021-02-01

  

  Recently, we have observed that pharmacological PPARα and PPARβ/δ activation regulates the expression of genes involved in FA metabolism such as FAT/CD36, CPT1, LCAD and MCAD in Sertoli cells. We have also observed that PPARβ/δ activation can simultaneously regulate the expression of the above-menti

• Characterization factor is another variable suggested in the

  2021-01-30

  

  Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain

• The regression also revealed a significant association betwe

  2021-01-30

  

  The regression also revealed a significant association between admission selectivity (SELECT) and exam pass rate (PASS%) (p Deferiprone serve as an indicator of a student’s ability to learn and their aptitude for academic success. These same qualities likely enable more selective schools to design m

• liothyronine sodium receptor Autophagy is a dynamic process

  2021-01-30

  

  Autophagy is a dynamic process that primarily involves autophagosome formatting and lysosomal degradation, and these processes are controlled by autophagy-related genes (Atg) (Klionsky et al., 2012). The related protein SQSTM1/p62 (sequestosome 1) importantly serves as a signalling director in sever

• br Conclusion br Experimental NMR

  2021-01-30

  

  Conclusion Experimental NMR spectra were recorded on a Jeol spectrometer at either 270 or 400 MHz for 1H spectra and either 68 or 100 MHz for 13C spectra. All chemical shifts are quoted in ppm relative to tetramethylsilane. In the assignment of signals the abbreviation DHN is used for 2,3-dihy

• To our knowledge this is the first report

  2021-01-30

  

  To our knowledge, this is the first report of an oncocytoma expressing alpha-enolase or causing autoimmune retinopathy and optic neuropathy. Although generally considered benign, oncocytomas have rarely been associated with paraneoplastic syndromes, including tumor-induced hypertension, erythrocytos

• br Introduction As a serine proteinase and a

  2021-01-30

  

  Introduction As a serine proteinase and a sub-family of the chymotrypsin-like proteinase, Glutamyl endopeptidase (GE), which is mainly found in Bacillus species, specifically cleaves negatively charged amino Derquantel residues (Glu/Asp) (Yokoi et al., 2001). Madsen et al. (Madsen & Qvist, 1997)

15614 records 737/1041 page Previous Next First page 上5页 736737738739740 下5页 Last page