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In the particular case of metals
2020-07-21

In the particular case of metals, several authors showed that AChE inhibition is somewhat contradictory and even questionable (Frasco et al., 2005, Nunes et al., 2005, Sáenz et al., 2010). Uranium is a particular metal, and one that has been shown to complex with several biologically important prote
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Building s constructional elements should be able to
2020-07-21

Building\'s constructional elements should be able to protect residents from the negative effect of noise caused by surroundings [19]. The World Health Organization estimates that each year more than one million Healthy Life Years are lost in the European Union member states and other Western Europe
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Although it remains an unsettled issue evidence favors that
2020-07-21

Although it remains an unsettled issue, evidence favors that the endothelin ETA IWP-L6 synthesis may play a more important pathological role. While both endothelin ETA and ETB receptors are found in most tissues, endothelin ETA receptor is the predominant receptor responsible for the vasoconstricti
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Estrogen treatment in postmenopausal women requires
2020-07-21

Estrogen treatment in postmenopausal women requires combination with a progestogen in order to prevent endometrial stimulation. This is not necessary, however, with tibolone as progestogenic activity is associated with its Δ4-metabolite that is formed in the liver, as well as locally in the endometr
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The quaternary structure of many of the
2020-07-21

The quaternary structure of many of the family B members (i.e., secretin, glucagon, glucagon-like peptide and BIBW2992 receptors) have been actively studied and it has been demonstrated that they can form homodimers/oligomers (Gao et al., 2009; Ng & Chow, 2015; Ng, Lee, & Chow, 2013). Harikumar, Pi
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In the present study synthesis of
2020-07-21

In the present study, synthesis of Bi2MoO6 nanoplates via DNA-templated hydrothermal method has been undertaken. The synthesis was done through the hydrothermal method by means of the reaction of bismuth nitrate pentahydrate (Bi(NO3)3·5H2O) with sodium molybdate dihydrate (Na2MoO4·2H2O) precursor in
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In this paper we describe a facile and universal
2020-07-20

In this paper, we describe a facile and universal method for in situ crosslinking of DNA micelles, using spherically directed reduction of metal ions. As shown in Scheme 1A, a single-stranded DNA (ssDNA) consisting of a ligand domain, a template domain, and a lipid domain was designed as a monomer t
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Several reports have exploited the
2020-07-20

Several reports , , , , have exploited the application of HRM for detecting differentially methylated DNA. Even though DNA methylation analysis by HRM cannot determine the methylation status of individual CpGs, it does provide a robust and inexpensive method to differentiate DNA based on the overal
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Possibly there are similarities among euphorb plant species
2020-07-20

Possibly there are similarities among euphorb plant species but extraction of the PPM-18 mg present in the microsomal fraction is needed for testing their preferences for substrates. Although R. communis, E. lathyris and E. lagascae belong to the same family, the DGAT activity of their microsomal p
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Some mechanistic experiments performed in the early s by Ong
2020-07-20

Some mechanistic experiments performed in the early 2000s by Ongusaha et al. [78], suggest that DDR1 induction protects hcv protease inhibitors from apoptosis in a p53-dependent manner, and that impairment of DDR1 expression or function leads to a pronounced increase of DNA damage-induced apoptosis
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Regarding the mechanism of action of CRF several studies
2020-07-20

Regarding the mechanism of action of CRF, several studies have shown that low doses of CRF may preferentially activate CRF1 receptors in glutamatergic projection neurons, serotoninergic neurons or glutamatergic collaterals in the medial prefrontal cortex (Vertes, 2004). Indeed, prosencephalic inacti
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In summary EP signaling modulates
2020-07-20

In summary, EP1 signaling modulates heteromeric kainate receptors at multiple steps, both sensitizing mice to kainate-evoked status epilepticus and, separately, exacerbating the downstream consequences of status epilepticus. These results, together with those of Serrano et al. (2011) and Jiang et a
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Several of the keloid like lesions seen
2020-07-17

Several of the keloid-like lesions seen in these individuals were pigmented. It is of potential relevance that genetic variants in DDR1 [MIM: 600408] have been associated with vitiligo, and DDR1 activation is involved when L-817,818 are attached to collagen-IV fibers. Because DDR1 and DDR2 are para
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Following Duncan as a ritualized site
2020-07-17

Following Duncan (1995), as a ritualized site Tyne Cot provides an opportunity for individual tourists to conduct their own acts of remembrance (Edensor, 2000, Iles, 2006). The analysis has also shown that individual acts of writing particular words and phrases in the visitor books are socially shar
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To simulate the inhibition of the enzyme
2020-07-17

To simulate the inhibition of the enzyme by organophosphorus, carbamate insecticides or nerve agents, a reversible cholinesterase inhibitor physostigmine was used for most experiments for safety reasons. However, the results of the measurements were verified using the soman organophosphate, which is
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